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Figure 3 BDG Induces Glutathione Synthesis and Metabolism in Human Monocytes Given that glutathione metabolism was enriched in the gene ontology of upregulated genes and that glutathione synthesis/metabolism are regulated by NRF2, a TF whose gene expression is increased after BDG exposure and motif is enriched in all the ATAC-seq groups, we sought to investigate the effect of BDG on this pathway in human monocytes ( Figure 4A )

Skin inflammation Decreases inflammatory discoloration, redness, and blotchy patches by neutralizing free radicals

Blood glucose and fasting insulin levels were markedly elevated in HFD-fed mice and showed a higher HOMA insulin resistance index (Fig

Methods Animal studies All animal studies were performed according to protocols approved by the University Committee on Animal Resources at the University of Rochester Medical Center

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